N in the reduced intake categories, those who have been inside the prime quartile of total fat intake had shorter TLs, although the linear trend was not considerable (Table 2; Ptrend =0.09). In distinct, SFA intake ( of energy) was inversely linked with TL. Compared with girls in the reduce intake categories, people who consumed the highest percentage of energy from SFAs (median: 14.0 ) also had shorter TLs [mean: 3.98 kb (95 CI: 3.86, 4.09 kb); Ptrend = 0.017]. Intakes ofTABLE 2 Peripheral leukocyte telomere length as outlined by quartiles of dietary fat intake within a subsample of postmenopausal women from the WHIDietary fat intake Nutrient and telomere length Total fat, of power Telomere length, kb Model 1 Model 2 SFAs, of power Telomere length, kb Model 1 Model two MUFAs, of energy Telomere length, kb Model 1 Model two PUFAs, of power Telomere length, kb Model 1 Model 2 Quartile 1 21.7 4.07 (three.99, four.16) 4.12 (4.00, 4.23) six.six four.09 (four.00, four.17) 4.13 (4.01, four.24) 7.9 four.3-Methoxy-4-pyridinamine In stock 08 (three.99, 4.16) 4.12 (4.00, four.23) 4.four four.05 (3.96, four.14) four.10 (three.98, four.21) Quartile two 28.4 four.05 (three.97, four.14) 4.12 (4.01, four.23) 9.0 4.15 (4.06, four.23) 4.18 (4.07, four.29) 10.6 4.02 (3.93, 4.10) 4.07 (3.96, four.18) 5.8 4.06 (3.98, four.15) 4.10 (3.99, four.20) Quartile three 34.two four.11 (four.02, four.19) 4.16 (4.05, 4.26) 11.1 four.03 (three.95, 4.12) 4.07 (three.96, four.18) 13.1 4.12 (4.03, four.20) four.16 (4.05, four.26) 7.1 4.06 (three.97, four.14) four.11 (4.00, four.21) Quartile 4 41.9 3.99 (3.90, 4.07) 3.98 (3.87, four.09) 14.0 three.96 (three.87, 4.04) three.98 (3.86, 4.09) 16.3 4.01 (3.93, four.10) four.02 (three.91, four.13) 9.three 4.05 (three.96, four.14) 4.05 (three.95, four.16) 0.26 0.09 Ptrend0.010 0.0.57 0.0.97 0.1 Values for telomere length are leastsquare means (95 CIs). Values for every single nutrient are median intakes on the nutrient in accordance with quartiles. Model 1: adjusted for age (y, continuous); model two: adjusted for age (y, continuous), raceethnicity (white, black, Hispanic, Asian/ Pacific Islander), BMI (#25, .250, .305, .35 kg/m2), smoking (in no way, former, current smoker), day-to-day alcohol intake (#0.01, .0.010.1, .0.1, .2 g/d), diabetes case within the key casecontrol study (yes, no), physical activity (0, .0, .50, .20 metabolic equivalent hours/wk), and each day intakes of power (kcal, continuous), fruit and vegetables (medium serving [;170 g], continuous), vitamin C (mg, continuous), vitamin E (IU, continuous), selenium (mg, continuous), and bcarotene (mg, continuous). WHI, Ladies Wellness Initiative. two P values for linear trend have been obtained by including the median intake levels of every group as continuous variables in the regression models.Fatty acid intake and telomere lengthTABLE 3 Peripheral leukocyte telomere length as outlined by quartiles of person dietary SFA intake within a subsample of postmenopausal females in the WHIDietary SFA intake SFA and telomere length SMSFAs, of energy Telomere length, kb Model 1 Model 2 Butyric acid (4:0), of energy Telomere length, kb Model 1 Model two Hexanoic acid (six:0), of energy Telomere length, kb Model 1 Model 2 Octanoic acid (8:0), of energy Telomere length, kb Model 1 Model two Decanoic acid (10:0), of power Telomere length, kb Model 1 Model two Lauric acid (12:0), of power Telomere length, kb Model 1 Model two LSFAs, of power Telomere length, kb Model 1 Model two Myristic acid (14:0), of power Telomere length, kb Model 1 Model two Palmitic acid (16:0), of power Telomere length, kb Model 1 Model 2 Margaric acid (17:0), of power Telomere length, kb Model 1 Model two Stearic acid (18:0), of power Telomere l.Buy1217500-64-5 PMID:22664133
