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Redox Biology two (2014) 296?Contents lists readily available at ScienceDirectRedox Biologyjournal homepage: elsevier/locate/redoxReview ArticleDietary restriction in cerebral bioenergetics and redox stateIgnacio Amigo, Alicia J. Kowaltowski nDepartamento de Bioqu ica, Instituto de Qu ica, Universidade de S Paulo, SP, Brazilart ic l e i nf oArticle history: Received 30 December 2013 Accepted 30 December 2013 Offered on the web 11 January 2014 Keywords and phrases: Caloric restriction Neurological diseases Mitochondria Energy metabolisma b s t r a c tThe brain has a central role in the regulation of energy stability in the organism. It is actually the organ using the highest energetic demands, essentially the most susceptible to energy deficits, and is responsible for coordinating behavioral and physiological responses related to meals foraging and intake. Dietary interventions have already been shown to become an extremely impact.
